Now showing items 1-5 of 5

    • Dopamine Signaling Is Essential for Precise Rates of Locomotion by C. elegans 

      Omura, Daniel T.; Clark, Damon A.; Samuel, Aravinthan DT; Horvitz, H. Robert (Public Library of Science, 2012)
      Dopamine is an important neuromodulator in both vertebrates and invertebrates. We have found that reduced dopamine signaling can cause a distinct abnormality in the behavior of the nematode C. elegans, which has only eight ...
    • The Fourth Law of Behavior Genetics 

      Chabris, C. F.; Lee, J. J.; Cesarini, D.; Benjamin, D. J.; Laibson, David I. (SAGE Publications, 2015)
      Behavior genetics is the study of the relationship between genetic variation and psychological traits. Turkheimer (2000) proposed “Three Laws of Behavior Genetics” based on empirical regularities observed in studies of ...
    • Reph, a Regulator of Eph Receptor Expression in the Drosophila melanogaster Optic Lobe 

      Dearborn, Richard E.; Dai, Yong; Reed, Brian; Karian, Tamar; Gray, Jessica; Kunes, Samuel M. (Public Library of Science, 2012)
      Receptors of the Eph family of tyrosine kinases and their Ephrin ligands are involved in developmental processes as diverse as angiogenesis, axon guidance and cell migration. However, our understanding of the Eph signaling ...
    • Similar Genetic Mechanisms Underlie the Parallel Evolution of Floral Phenotypes 

      Zhang, Wenheng; Kramer, Elena M.; Davis, Charles Cavender (Public Library of Science, 2012)
      The repeated origin of similar phenotypes is invaluable for studying the underlying genetics of adaptive traits; molecular evidence, however, is lacking for most examples of such similarity. The floral morphology of ...
    • Stochastic Expression of the Interferon-β Gene 

      Zhao, Mingwei; Zhang, Jiangwen; Phatnani, Hemali; Scheu, Stefanie; Maniatis, Thomas P. (Public Library of Science, 2012)
      Virus infection of mammalian cells induces the production of high levels of type I interferons (IFNα and β), cytokines that orchestrate antiviral innate and adaptive immunity. Previous studies have shown that only a fraction ...