Browsing FAS Scholarly Articles by Keyword "molecular neuroscience"

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    • Dopamine Signaling Is Essential for Precise Rates of Locomotion by C. elegans 

      Omura, Daniel T.; Clark, Damon A.; Samuel, Aravinthan DT; Horvitz, H. Robert (Public Library of Science, 2012)
      Dopamine is an important neuromodulator in both vertebrates and invertebrates. We have found that reduced dopamine signaling can cause a distinct abnormality in the behavior of the nematode C. elegans, which has only eight ...

    • Quantitative and functional interrogation of parent-of-origin allelic expression biases in the brain 

      Perez, Julio D; Rubinstein, Nimrod D; Fernandez, Daniel E; Santoro, Stephen W; Needleman, Leigh A; Ho-Shing, Olivia; Choi, John J; Zirlinger, Mariela; Chen, Shau-Kwaun; Liu, Jun S; Dulac, Catherine (eLife Sciences Publications, Ltd, 2015)
      The maternal and paternal genomes play different roles in mammalian brains as a result of genomic imprinting, an epigenetic regulation leading to differential expression of the parental alleles of some genes. Here we ...

    • Reph, a Regulator of Eph Receptor Expression in the Drosophila melanogaster Optic Lobe 

      Dearborn, Richard E.; Dai, Yong; Reed, Brian; Karian, Tamar; Gray, Jessica; Kunes, Samuel M. (Public Library of Science, 2012)
      Receptors of the Eph family of tyrosine kinases and their Ephrin ligands are involved in developmental processes as diverse as angiogenesis, axon guidance and cell migration. However, our understanding of the Eph signaling ...