Cavum septum pellucidum in monozygotic twins discordant for combat exposure: relationship to posttraumatic stress disorder

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Cavum septum pellucidum in monozygotic twins discordant for combat exposure: relationship to posttraumatic stress disorder

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Title: Cavum septum pellucidum in monozygotic twins discordant for combat exposure: relationship to posttraumatic stress disorder
Author: May, Flavia S; Chen, Q.Cece; Gilbertson, Mark; Shenton, Martha Elizabeth ORCID  0000-0003-4235-7879 ; Pitman, roger Keith

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Citation: May, Flavia S, Q.Cece Chen, Mark W Gilbertson, Martha E Shenton, and Roger K Pitman. 2004. Cavum Septum Pellucidum in Monozygotic Twins Discordant for Combat Exposure: Relationship to Posttraumatic Stress Disorder. Biological Psychiatry 55, no. 6: 656–658. doi:10.1016/j.biopsych.2003.09.018.
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Abstract: Background

Abnormally large cavum septum pellucidum has been reported in posttraumatic stress disorder; however, the origin of this association is uncertain.
Methods: We utilized magnetic resonance imaging to measure cavum septum pellucidum in pairs of identical twins discordant for combat exposure in Vietnam. Results: Presence of abnormal cavum septum pellucidum was significantly correlated between exposed and unexposed twins, indicating that it is partially determined by heredity and/or shared environment. There was a greater proportion of cavum septum pellucidum in combat-exposed twins with posttraumatic stress disorder and their noncombat-exposed co-twins. Conclusions: The presence of abnormally large cavum septum pellucidum is a familial vulnerability factor for posttraumatic stress disorder.
Published Version: doi:10.1016/j.biopsych.2003.09.018
Other Sources: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2794416/
Terms of Use: This article is made available under the terms and conditions applicable to Other Posted Material, as set forth at http://nrs.harvard.edu/urn-3:HUL.InstRepos:dash.current.terms-of-use#LAA
Citable link to this page: http://nrs.harvard.edu/urn-3:HUL.InstRepos:28527471
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