Browsing Harvard Central Administration and University Research Centers by Author "Garber, Alan"
Now showing items 1-20 of 73
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Antibiotic exposure and resistance in mixed bacterial populations
Garber, Alan M (Elsevier, 1987)Antibiotic use is often blamed for increases in the prevalence of infections due to antibiotic-resistant bacteria. This paper clarifies the effects of antibiotic exposure on bacterial antibiotic resistance by developing ... -
Can technology assessment control health spending?
Garber, Alan M (Project Hope, 1994)Because medical technology is the most important controllable component of health spending growth, the success of strategies for limiting spending growth depends upon their impact on technology dissemination. Technology ... -
Case mix, costs, and outcomes — differences between faculty and community services in a university hospital
Garber, Alan M; Fuchs, Victor R.; Silverman, James F. (Massachusetts Medical Society, 1984)To gain insight into the possible consequences of prospective payment for university hospitals, we studied 2025 admissions to the faculty and community services of a university hospital, measuring differences in case mix, ... -
A computer program for statistically-based decision analysis
Polaschek, Jeanette X.; Lenert, Leslie A.; Garber, Alan M (American Medical Informatics Association, 1990)The majority of patients with coronary artery disease do not fall into the well defined populations from randomized clinical trials. Observational databases contain a rich source of information that could be used by ... -
The confirmatory trial in comparative-effectiveness research
Garber, Alan M; Hlatky, Mark A. (Massachusetts Medical Society, 2009) -
Consequences of health trends and medical innovation for the future elderly
Goldman, Dana P.; Shang, Baoping; Bhattacharya, Jayanta; Garber, Alan M; Hurd, Michael; Joyce, Geoffrey F.; Lakdawalla, Darius N.; Panis, Constantijn; Shekelle, Paul G. (Project HOPE, 2005)Recent innovations in biomedicine seem poised to revolutionize medical practice. At the same time, disease and disability are increasing among younger populations. This paper considers how these confluent trends will affect ... -
Coping with chronic disease? Chronic disease and disability in elderly American population 1982-1999
Aranovich, Gabriel; Bhattacharya, Jay; Garber, Alan M; MaCurdy, Thomas E. (National Bureau of Economic Research Inc, 2009)It is well known that disability rates among the American elderly have declined over the past decades. The cause of this decline is less well established. In this paper, we test one important possible explanation--that the ... -
Corporate treatment for the ills of academic medicine
Garber, Alan M (Massachusetts Medical Society, 2004) -
Cost effectiveness of alternative imaging strategies for the diagnosis of small-bowel crohn's disease
Levesque, Barrett G.; Cipriano, Lauren E.; Chang, Steven L.; Lee, Keane K.; Owens, Douglas K.; Garber, Alan M (Elsevier, 2010)Background & Aims The cost effectiveness of alternative approaches to the diagnosis of small-bowel Crohn's disease is unknown. This study evaluates whether computed tomographic enterography (CTE) is a cost-effective ... -
The cost of VA-sponsored research
Barnett, Paul G.; Garber, Alan M (Association of American Medical Colleges, 1996)BACKGROUND: Under pressures to reduce health care costs, clinical income is a shrinking source of support for research. Such pressures also threaten research at the medical centers of the Department of Veterans Affairs ... -
A cost-effectiveness analysis of adjuvant trastuzumab tegimens in early HER2/neu-positive breast cancer
Kurian, Allison W.; Thompson, Rebecca Newton; Gaw, Allison F.; Arai, Sally; Ortiz, Rafael; Garber, Alan M (American Society of Clinical Oncology, 2007)Purpose One-year adjuvant trastuzumab (AT) therapy, with or without anthracyclines, increases disease-free and overall survival in early-stage HER2/neu-positive breast cancer. We sought to evaluate the cost effectiveness ... -
Cost-effectiveness and cost-benefit analysis of using methotrexate vs goeckerman therapy for psoriasis
Chen, Suephy; Shaheen, Allison; Garber, Alan M (American Medical Association, 1998)Design Net benefit and cost-effectiveness depend on the costs, efficacy, and utilities of therapy. Utilities are quantitative measures of patient preferences. We obtained costs by using resource-based accounting techniques. ... -
Cost-effectiveness and evidence evaluation as criteria for coverage policy
Garber, Alan M (Project HOPE, 2004)Private health plans and government health insurance programs in the United States base their coverage decisions on evidence criteria, rather than explicit cost-effectiveness criteria. As health spending continues to grow ... -
Cost-effectiveness of 3 methods to enhance the sensitivity of Papanicolaou testing
Brown, Adalsteinn D.; Garber, Alan M (American Medical Association, 1999)Context ThinPrep, AutoPap, and Papnet are 3 new technologies that increase the sensitivity and cost of cervical cancer screening. Objective To estimate the cost-effectiveness of these technological enhancements to ... -
Cost-effectiveness of androgen suppression therapies in advanced prostate cancer
Bayoumi, Ahmed M.; Garber, Alan M; Brown, Adalsteinn D. (Oxford University Press, 2000)Background: The costs and side effects of several antiandrogen therapies for advanced prostate cancer differ substantially. We estimated the cost-effectiveness of antiandrogen therapies for advanced prostate cancer. Methods: ... -
Cost-effectiveness of automated external defibrillators on airlines
Groeneveld, Peter W.; Kwong, Jeanne L.; Liu, Yueyi; Rodriguez, Adam J.; Jones, Michael P.; Sanders, Gillian D.; Garber, Alan M (American Medical Association, 2001)Context: Installation of automated external defibrillators (AEDs) on passenger aircraft has been shown to improve survival of cardiac arrest in that setting, but the cost-effectiveness of such measures has not been ... -
Cost-effectiveness of dabigatran compared with warfarin for stroke prevention in atrial fibrillation
Freeman, James V.; Zhu, Ruo P.; Owens, Douglas K.; Garber, Alan M; Hutton, David W.; Go, Alan S.; Wang, Paul J.; Turakhia, Mintu P. (American College of Physicians, 2011)Background: Warfarin reduces the risk for ischemic stroke in patients with atrial fibrillation (AF) but increases the risk for hemorrhage. Dabigatran is a fixed-dose, oral direct thrombin inhibitor with similar or reduced ... -
Cost-effectiveness of screening BRCA1/2 mutation carriers with breast magnetic resonance imaging
Plevritis, Sylvia K.; Kurian, Allison W.; Sigal, Bronislava M.; Daniel, Bruce L.; Ikeda, Debra M.; Stockdale, Frank E.; Garber, Alan M (American Medical Association, 2006)Context: Women with inherited BRCA1/2 mutations are at high risk for breast cancer, which mammography often misses. Screening with contrast-enhanced breast magnetic resonance imaging (MRI) detects cancer earlier but increases ... -
The cost-effectiveness of therapy with teriparatide and alendronate in women with severe osteoporosis
Liu, Hau; Michaud, Kaleb; Nayak, Smita; Karpf, David B.; Owens, Douglas K.; Garber, Alan M (American Medical Association, 2006)Background Teriparatide is a promising new agent for the treatment of osteoporosis. Methods The objective of this study was to evaluate the cost-effectiveness of teriparatide-based strategies compared with alendronate ... -
Costs and benefits of prenatal screening for cystic fibrosis
Garber, Alan M; Fenerty, Joseph P. (Lippincott Williams & Wilkins, 1991)