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    • Integration of genomics and histology revises diagnosis and enables effective therapy of refractory cancer of unknown primary with PDL1 amplification 

      Gröschel, Stefan; Bommer, Martin; Hutter, Barbara; Budczies, Jan; Bonekamp, David; Heining, Christoph; Horak, Peter; Fröhlich, Martina; Uhrig, Sebastian; Hübschmann, Daniel; Geörg, Christina; Richter, Daniela; Pfarr, Nicole; Pfütze, Katrin; Wolf, Stephan; Schirmacher, Peter; Jäger, Dirk; von Kalle, Christof; Brors, Benedikt; Glimm, Hanno; Weichert, Wilko; Stenzinger, Albrecht; Fröhling, Stefan (Cold Spring Harbor Laboratory Press, 2016)
      Identification of the tissue of origin in cancer of unknown primary (CUP) poses a diagnostic challenge and is critical for directing site-specific therapy. Currently, clinical decision-making in patients with CUP primarily ...