Browsing HMS Scholarly Articles by Author "Beausoleil, Sean A"

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    • Survey of Activated FLT3 Signaling in Leukemia 

      Gu, Ting-lei; Nardone, Julie; Loriaux, Marc; Tucker, Meghan; Kornhauser, Jon; Ren, Jianmin; MacNeill, Joan; Druker, Brian J.; Heinrich, Michael C.; Rush, John; Polakiewicz, Roberto D.; Villén, Judit; Gygi, Steven P.; Beausoleil, Sean A; Wang, Yi (Public Library of Science, 2011)
      Activating mutations of FMS-like tyrosine kinase-3 (FLT3) are found in approximately 30% of patients with acute myeloid leukemia (AML). FLT3 is therefore an attractive drug target. However, the molecular mechanisms by which ...