Now showing items 1-3 of 3

    • A new paradigm for transcription factor TFIIB functionality 

      Gelev, Vladimir; Zabolotny, Janice M.; Lange, Martin; Hiromura, Makoto; Yoo, Sang Wook; Orlando, Joseph S.; Kushnir, Anna; Horikoshi, Nobuo; Paquet, Eric; Bachvarov, Dimcho; Schaffer, Priscilla A.; Usheva, Anny (Nature Publishing Group, 2014)
      Experimental and bioinformatic studies of transcription initiation by RNA polymerase II (RNAP2) have revealed a mechanism of RNAP2 transcription initiation less uniform across gene promoters than initially thought. However, ...
    • Rho-kinase Regulates Energy Balance by Targeting Hypothalamic Leptin Receptor Signaling 

      Huang, Hu; Kong, Dong; Byun, Kyung Hee; Ye, Chianping; Koda, Shuichi; Lee, Dae Ho; Oh, Byung-Chul; Lee, Sam Whan; Lee, Bonghee; Zabolotny, Janice M.; Kim, Min Seon; Bjørbæk, Christian; Lowell, Bradford Barr; Kim, Young-Bum (2012)
      Leptin regulates energy balance. However, knowledge of the critical intracellular transducers of leptin signaling remains incomplete. Here we report that Rho-kinase 1 (ROCK1) regulates leptin action on body weight homeostasis ...
    • Specificity and Heterogeneity of Terahertz Radiation Effect on Gene Expression in Mouse Mesenchymal Stem Cells 

      Alexandrov, Boian S.; Phipps, M. Lisa; Alexandrov, Ludmil B.; Booshehri, Layla G.; Erat, Anna; Zabolotny, Janice M.; Mielke, Charles H.; Chen, Hou-Tong; Rodriguez, George; Rasmussen, Kim Ø.; Martinez, Jennifer S.; Bishop, Alan R.; Usheva, Anny (Nature Publishing Group, 2013)
      We report that terahertz (THz) irradiation of mouse mesenchymal stem cells (mMSCs) with a single-frequency (SF) 2.52 THz laser or pulsed broadband (centered at 10 THz) source results in irradiation specific heterogenic ...