Now showing items 1-2 of 2

    • Contraction stimulates muscle glucose uptake independent of atypical PKC 

      Yu, Haiyan; Fujii, Nobuharu L; Toyoda, Taro; An, Ding; Farese, Robert V; Leitges, Michael; Hirshman, Michael F; Mul, Joram D; Goodyear, Laurie J (John Wiley & Sons, Ltd, 2015)
      Exercise increases skeletal muscle glucose uptake, but the underlying mechanisms are only partially understood. The atypical protein kinase C (PKC) isoforms λ and ζ (PKC-λ/ζ) have been shown to be necessary for insulin-, ...
    • Loss of BMP receptor type 1A in murine adipose tissue attenuates age-related onset of insulin resistance 

      Schulz, Tim J.; Graja, Antonia; Huang, Tian Lian; Xue, Ruidan; An, Ding; Poehle-Kronawitter, Sophie; Lynes, Matthew D.; Tolkachov, Alexander; O’Sullivan, Lindsay E.; Hirshman, Michael F.; Schupp, Michael; Goodyear, Laurie J.; Mishina, Yuji; Tseng, Yu-Hua (Springer Berlin Heidelberg, 2016)
      Aims/hypothesis Adipose tissue dysfunction is a prime risk factor for the development of metabolic disease. Bone morphogenetic proteins (BMPs) have previously been implicated in adipocyte formation. Here, we investigate ...