Browsing HMS Scholarly Articles by Author "Brion, Marie Jo A."

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    • Mining the Human Phenome Using Allelic Scores That Index Biological Intermediates 

      Evans, David M.; Brion, Marie Jo A.; Paternoster, Lavinia; Kemp, John P.; McMahon, George; Munafò, Marcus; Whitfield, John B.; Medland, Sarah E.; Montgomery, Grant W.; Timpson, Nicholas J.; St. Pourcain, Beate; Lawlor, Debbie A.; Martin, Nicholas G.; Dehghan, Abbas; Hirschhorn, Joel; Davey Smith, George (Public Library of Science, 2013)
      It is common practice in genome-wide association studies (GWAS) to focus on the relationship between disease risk and genetic variants one marker at a time. When relevant genes are identified it is often possible to implicate ...