Browsing HMS Scholarly Articles by Title
Now showing items 4926-4945 of 17922
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Ebp1 Sumoylation, Regulated by TLS/FUS E3 Ligase, Is Required for Its Anti-Proliferative Activity
(Nature Publishing Group, 2010)Ebp1, an ErbB3 receptor-binding protein, inhibits cell proliferation and acts as a putative tumor suppressor. Ebp1 translocates into the nucleus and functions as a transcription co-repressor for E2F-1. Here, we show that ... -
EBV-Positive Diffuse Large B-Cell Lymphoma in a Human T-Lymphotropic Virus Type 1 Carrier
(Springer Science and Business Media LLC, 2009-07-06)The development of B-cell lymphomas has been seldom described in HTLV-1 carriers. We present the case of an elderly Peruvian HTLV-1 carrier who was diagnosed with EBV-positive diffuse large B-cell lymphoma. Despite an ... -
eccDNAs are apoptotic products with high innate immunostimulatory activity
(Springer Science and Business Media LLC, 2021-10-20) -
Ecdysone Signaling at Metamorphosis Triggers Apoptosis of Drosophila Abdominal Muscles
(Elsevier BV, 2013-11-15)One of the most dramatic examples of programmed cell death occurs during Drosophila metamorphosis, when most of the larval tissues are destroyed in a process termed histolysis. Much of our understanding of this process ... -
ECG Morphological Variability in Beat Space for Risk Stratification After Acute Coronary Syndrome
(Blackwell Publishing Ltd, 2014)Background: Identification of patients who are at high risk of adverse cardiovascular events after an acute coronary syndrome (ACS) remains a major challenge in clinical cardiology. We hypothesized that quantifying variability ... -
Echocardiographic Predictors of Mortality in Patients with Pulmonary Hypertension and Cardiopulmonary Comorbidities
(Public Library of Science, 2015)Objective: We aimed to identify the echocardiographic measures associated with survival in a patient population with a high prevalence of co-morbid cardiovascular and pulmonary disease that have significantly elevated ... -
Echocardiography Practice, Training and Accreditation in the Intensive Care: Document for the World Interactive Network Focused on Critical Ultrasound (WINFOCUS)
(BioMed Central, 2008)Echocardiography is increasingly used in the management of the critically ill patient as a non-invasive diagnostic and monitoring tool. Whilst in few countries specialized national training schemes for intensive care unit ... -
Echocardiography-derived left ventricular end-systolic regional wall stress and matrix remodeling after experimental myocardial infarction
(Elsevier BV, 1999)OBJECTIVES We tested the hypothesis that regional end-systolic left ventricular (ESLV) wall stress is associated with extracellular matrix remodeling activity after myocardial infarction (MI). BACKGROUND Increased ... -
Ecological robustness of the gut microbiota in response to ingestion of transient food-borne microbes
(Nature Publishing Group, 2016)Resident gut microbes co-exist with transient bacteria to form the gut microbiota. Despite increasing evidence suggesting a role for transient microbes on gut microbiota function, the interplay between resident and transient ... -
Economic analysis of endovascular drug-eluting treatments for femoropopliteal artery disease in the UK
(BMJ Publishing Group, 2016)Objectives: To estimate the clinical and economic impact of drug-eluting endovascular treatment strategies for femoropopliteal artery disease compared with current standard of care. Design: Systematic literature search to ... -
Economic and Other Barriers to Adopting Recommendations to Prevent Childhood Obesity: Results of a Focus Group Study with Parents
(BioMed Central, 2009)Background: Parents are integral to the implementation of obesity prevention and management recommendations for children. Exploration of barriers to and facilitators of parental decisions to adopt obesity prevention ... -
The Economic Burden Attributable to a Child’s Inpatient Admission for Diarrheal Disease in Rwanda
(Public Library of Science, 2016)Background: Diarrhea is one of the leading causes of childhood morbidity and mortality. Hospitalization for diarrhea can pose a significant burden to health systems and households. The objective of this study was to estimate ... -
The Economic Consequences Of Mortality Amenable To High-Quality Health Care In Low- And Middle-Income Countries
(Health Affairs (Project Hope), 2018-06)We estimated deaths amenable to high-quality health care globally and then modeled the macroeconomic impact in low- and middle-income countries using two macroeconomic perspectives: a value-of-lost-output approach to project ... -
Economics of Malaria Prevention in US Travelers to West Africa
(Oxford University Press, 2013)Background. Pretravel health consultations help international travelers manage travel-related illness risks through education, vaccination, and medication. This study evaluated costs and benefits of that portion of the ... -
Ecstasy Exposure & Gender: Examining Components of Verbal Memory Functioning
(Public Library of Science, 2014)Objective: Studies have demonstrated verbal memory deficits associated with past year ecstasy use, although specific underlying components of these deficits are less understood. Further, prior research suggests potential ... -
Ecto-protein kinases and phosphatases: an emerging field for translational medicine
(BioMed Central, 2014)Progress in translational research has led to effective new treatments of a large number of diseases. Despite this progress, diseases including cancer and cardiovascular disorders still are at the top in death statistics ... -
Ectonucleotidases in Müller Glial Cells of the Rodent Retina: Involvement in Inhibition of Osmotic Cell Swelling
(Springer Netherlands, 2007)Extracellular nucleotides mediate glia-to-neuron signalling in the retina and are implicated in the volume regulation of retinal glial (Müller) cells under osmotic stress conditions. We investigated the expression and ... -
edgeRun: an R package for sensitive, functionally relevant differential expression discovery using an unconditional exact test
(Oxford University Press, 2015)Summary: Next-generation sequencing platforms for measuring digital expression such as RNA-Seq are displacing traditional microarray-based methods in biological experiments. The detection of differentially expressed genes ... -
Edgetic Perturbation Models of Human Inherited Disorders
(Nature Publishing Group, 2009)Cellular functions are mediated through complex systems of macromolecules and metabolites linked through biochemical and physical interactions, represented in interactome models as ‘nodes' and ‘edges', respectively. Better ... -
Editing of mouse and human immunoglobulin genes by CRISPR-Cas9 system
(Nature Publishing Group, 2016)Applications of the CRISPR-Cas9 system to edit the genome have widely expanded to include DNA gene knock-out, deletions, chromosomal rearrangements, RNA editing and genome-wide screenings. Here we show the application of ...