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Levels of Foxp3 in Regulatory T Cells Reflect Their Functional Status in Transplantation
(The American Association of Immunologists, 2008)
Foxp3 expressing CD4+CD25+ regulatory T cells (Tregs) have been shown to prevent allograft rejection in clinical and animal models of transplantation. However, the role of Foxp3 in regulating Treg function, and the kinetics ...