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An Integrated Strategy for Analyzing the Unique Developmental Programs of Different Myoblast Subtypes
(Public Library of Science, 2006)
An important but largely unmet challenge in understanding the mechanisms that govern the formation of specific organs is to decipher the complex and dynamic genetic programs exhibited by the diversity of cell types within ...
Preferred analysis methods for Affymetrix GeneChips revealed by a wholly defined control dataset
(BioMed Central, 2005)
Background: As more methods are developed to analyze RNA-profiling data, assessing their
performance using control datasets becomes increasingly important.
Results: We present a 'spike-in' experiment for Affymetrix ...
Computation-Based Discovery of Related Transcriptional Regulatory Modules and Motifs Using an Experimentally Validated Combinatorial Model
(Cold Spring Harbor Laboratory, 2002-07)
Gene expression is regulated by transcription factors that interact with cis-regulatory elements. Predicting these elements from sequence data has proven difficult. We describe here a successful computational search for ...