Obesity & Hypertension are Determinants of Poor Hemodynamic Control during Total Joint Arthroplasty: A Retrospective Review

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Obesity & Hypertension are Determinants of Poor Hemodynamic Control during Total Joint Arthroplasty: A Retrospective Review

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Title: Obesity & Hypertension are Determinants of Poor Hemodynamic Control during Total Joint Arthroplasty: A Retrospective Review
Author: Nwachukwu, Benedict Uchenna; Collins, Jamie E; Nelson, Emily P; Concepcion, Mercedes; Thornhill, Thomas Stone; Katz, Jeffrey Neil

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Citation: Nwachukwu, Benedict Uchenna, Jamie E. Collins, Emily P. Nelson, Mercedes Concepcion, Thomas Stone Thornhill, and Jeffrey Neil Katz. 2013. Obesity & hypertension are determinants of poor hemodynamic control during total joint arthroplasty: A retrospective review. BMC Musculoskeletal Disorders 14:20.
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Abstract: Background: Proper blood pressure control during surgical procedures such as total joint arthroplasty (TJA) is considered critical to good outcome. There is poor understanding of the pre-operative risk factors for poor intra-operative hemodynamic control. The purpose of this study is to identify risk factors for poor hemodynamic control during TJA. Methods: We performed a retrospective cohort analysis of 118 patients receiving TJA in the Dominican Republic. We collected patient demographic and comorbidity data. We developed an a priori definition for poor hemodynamic control: 1) Mean arterial pressure (MAP) <65% of preoperative MAP or 2) MAP >135% of preoperative MAP. We performed bivariate and multivariate analyses to identify risk factors for poor hemodynamic control during TJA. Results: Hypertension was relatively common in our study population (76 of 118 patients). Average preoperative mean arterial pressure was 109.0 (corresponding to an average SBP of 149 and DBP of 89). Forty-nine (41.5%) patients had intraoperative blood pressure readings consistent with poor hemodynamic control. Based on multi-variable analysis preoperative hypertension of any type (RR 2.9; 95% CI 1.3-6.3) and an increase in BMI (RR 1.2 per 5 unit increase; 95% CI 1.0-1.5) were significant risk factors for poor hemodynamic control. Conclusions: Preoperative hypertension and being overweight/obese increase the likelihood of poor blood pressure control during TJA. Hypertensive and/or obese patients warrant further attention and medical optimization prior to TJA. More work is required to elucidate the relationship between these risk factors and overall outcome.
Published Version: doi:10.1186/1471-2474-14-20
Other Sources: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3560179/pdf/
Terms of Use: This article is made available under the terms and conditions applicable to Other Posted Material, as set forth at http://nrs.harvard.edu/urn-3:HUL.InstRepos:dash.current.terms-of-use#LAA
Citable link to this page: http://nrs.harvard.edu/urn-3:HUL.InstRepos:10613671
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