Browsing FAS Scholarly Articles by Author "Maeder, Morgan L."

Now showing items 1-2 of 2

    • Efficient Delivery of Genome-Editing Proteins In Vitro and In Vivo 

      Zuris, John A.; Thompson, David B.; Shu, Yilai; Guilinger, John P.; Bessen, Jeffrey L.; Hu, Johnny H.; Maeder, Morgan L.; Joung, J. Keith; Chen, Zheng-Yi; Liu, David R. (2014)
      Efficient intracellular delivery of proteins is needed to fully realize the potential of protein therapeutics. Current methods of protein delivery commonly suffer from low tolerance for serum, poor endosomal escape, and ...

    • Robust, synergistic regulation of human gene expression using TALE activators 

      Maeder, Morgan L.; Linder, Samantha J.; Reyon, Deepak; Angstman, James F.; Fu, Yanfang; Sander, Jeffry D.; Joung, J. Keith (2013)
      Artificial transcription activator-like (TAL) effector-based activators (TALE activators) have broad utility but previous studies suggest that these monomeric proteins often possess low activities. Here we demonstrate that ...