Browsing HMS Scholarly Articles by Author "Beaver, John E."

Now showing items 1-2 of 2

    • A Genome-Wide Gene Function Prediction Resource for Drosophila melanogaster 

      Yan, Han; Venkatesan, Kavitha; Beaver, John E.; Klitgord, Niels; Yildirim, Muhammed; Hao, Tong; Hill, David E.; Cusick, Michael E.; Perrimon, Norbert; Roth, Frederick P.; Vidal, Marc; Provart, Nicholas James (Public Library of Science, 2010)
      Predicting gene functions by integrating large-scale biological data remains a challenge for systems biology. Here we present a resource for Drosophila melanogaster gene function predictions. We trained function-specific ...

    • Novel cardiovascular gene functions revealed via systematic phenotype prediction in zebrafish 

      Musso, Gabriel; Tasan, Murat; Mosimann, Christian; Beaver, John E.; Plovie, Eva; Carr, Logan A.; Chua, Hon Nian; Dunham, Julie; Zuberi, Khalid; Rodriguez, Harold; Morris, Quaid; Zon, Leonard; Roth, Frederick P.; MacRae, Calum A. (Company of Biologists, 2014)
      Comprehensive functional annotation of vertebrate genomes is fundamental to biological discovery. Reverse genetic screening has been highly useful for determination of gene function, but is untenable as a systematic approach ...