Browsing HMS Scholarly Articles by Title
Now showing items 8693-8712 of 17928
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Increasing fMRI Sampling Rate Improves Granger Causality Estimates
(Public Library of Science, 2014)Estimation of causal interactions between brain areas is necessary for elucidating large-scale functional brain networks underlying behavior and cognition. Granger causality analysis of time series data can quantitatively ... -
Increasing Glucose 6-Phosphate Dehydrogenase Activity Restores Redox Balance in Vascular Endothelial Cells Exposed to High Glucose
(Public Library of Science, 2012)Previous studies have shown that high glucose increases reactive oxygen species (ROS) in endothelial cells that contributes to vascular dysfunction and atherosclerosis. Accumulation of ROS is due to dysregulated redox ... -
Increasing incidence associated with herpes zoster infection in British Columbia, Canada
(BioMed Central, 2016)Background: Recent studies have shown an increasing incidence of herpes zoster (HZ) infection, which may be related to the introduction of varicella vaccination programs in children. We examined the epidemiology and treatment ... -
Increasing the Availability and Consumption of Drinking Water in Middle Schools: A Pilot Study
(Centers for Disease Control and Prevention, 2011)Introduction: Although several studies suggest that drinking water may help prevent obesity, no US studies have examined the effect of school drinking water provision and promotion on student beverage intake. We assessed ... -
Increasing the efficiency of trial-patient matching: automated clinical trial eligibility Pre-screening for pediatric oncology patients
(BioMed Central, 2015)Background: Manual eligibility screening (ES) for a clinical trial typically requires a labor-intensive review of patient records that utilizes many resources. Leveraging state-of-the-art natural language processing (NLP) ... -
Increasing the Generalisability of Improvement Research with an Improvement Replication Programme
(BMJ Group, 2011)If a quality improvement is found effective in one setting, would the same effects be found elsewhere? Could the same change be implemented in another setting? These are just two of the ‘generalisation questions’ which ... -
Increasing Working Memory Load Reduces Processing of Cross-Modal Task-Irrelevant Stimuli Even after Controlling for Task Difficulty and Executive Capacity
(Frontiers Media S.A., 2016)The classic account of the load theory (LT) of attention suggests that increasing cognitive load leads to greater processing of task-irrelevant stimuli due to competition for limited executive resource that reduces the ... -
The incredible journey: From megakaryocyte development to platelet formation
(The Rockefeller University Press, 2013)Circulating blood platelets are specialized cells that prevent bleeding and minimize blood vessel injury. Large progenitor cells in the bone marrow called megakaryocytes (MKs) are the source of platelets. MKs release ... -
Increment Threshold Functions in Retinopathy of Prematurity
(The Association for Research in Vision and Ophthalmology, 2016)Purpose To assess scotopic background adaptation in subjects with a history of preterm birth and retinopathy of prematurity (ROP). Retinopathy of prematurity is known to have long-term effects on rod photoreceptor and rod ... -
Incremental Reduction in Risk of Death Associated with Use of Guideline-Recommended Therapies in Patients with Heart Failure: A Nested Case-Control Analysis of IMPROVE HF
(Blackwell Publishing Ltd, 2012)Background: Several therapies are guideline-recommended to reduce mortality in patients with heart failure (HF) and reduced left ventricular ejection fraction, but the incremental clinical effectiveness of these therapies ... -
Independent and Combined Effects of Dietary Weight Loss and Exercise on Leukocyte Telomere Length in Postmenopausal Women
(2013)Objective: Investigate the effects of 12 months of dietary weight loss and/or aerobic exercise on leukocyte telomere length in postmenopausal women. Design and Methods 439 overweight or obese women (50–75 y) were randomized ... -
Independent and Population-Specific Association of Risk Variants at the IRGM Locus with Crohn's Disease
(Oxford University Press, 2010)DNA polymorphisms in a region on chromosome 5q33.1 which contains two genes, immunity related GTPase related family, M (IRGM) and zinc finger protein 300 (ZNF300), are associated with Crohn's disease (CD). The deleted ... -
The independent association between parathyroid hormone levels and hyperuricemia: a national population study
(BioMed Central, 2012)Introduction: Increased frequencies of hyperuricemia and gout have been associated with primary hyperparathyroidism, and recent clinical trials of parathyroid hormone (PTH) have reported hyperuricemic adverse events. We ... -
Independent Component Analysis of Alzheimer's DNA Microarray Gene Expression Data
(BioMed Central, 2009)Background: Gene microarray technology is an effective tool to investigate the simultaneous activity of multiple cellular pathways from hundreds to thousands of genes. However, because data in the colossal amounts generated ... -
Independent Component Analysis-Based Classification of Alzheimer's Disease MRI Data
(IOS Press, 2011-05-30)There is an unmet medical need to identify neuroimaging biomarkers that is able to accurately diagnose and monitor Alzheimer's disease (AD) at very early stages and assess the response to AD-modifying therapies. To a certain ... -
Independent effects of sham laparotomy and anesthesia on hepatic microRNA expression in rats
(BioMed Central, 2014)Background: Studies on liver regeneration following partial hepatectomy (PH) have identified several microRNAs (miRNAs) that show a regulated expression pattern. These studies involve major surgery to access the liver, ... -
Independent Vascular and Cognitive Risk Factors for Postoperative Delirium
(Elsevier BV, 2007) -
Indication Alerts Intercept Drug Name Confusion Errors during Computerized Entry of Medication Orders
(Public Library of Science, 2014)Background: Confusion between similar drug names is a common cause of potentially harmful medication errors. Interventions to prevent these errors at the point of prescribing have had limited success. The purpose of this ... -
Indication for mild therapeutic hypothermia based on an initial Glasgow Coma Scale motor score
(BioMed Central, 2015)Although neurological evaluation using the Glasgow Coma Scale motor score is mandatory for post-cardiac arrest patients, further study is required to determine if this score can be used as an indicator for mild therapeutic ...