Browsing HMS Scholarly Articles by Keyword "intestine"

Now showing items 1-2 of 2

    • Claudin-2-dependent paracellular channels are dynamically gated 

      Weber, Christopher R; Liang, Guo Hua; Wang, Yitang; Das, Sudipto; Shen, Le; Yu, Alan S L; Nelson, Deborah J; Turner, Jerrold R (eLife Sciences Publications, Ltd, 2015)
      Intercellular tight junctions form selectively permeable barriers that seal the paracellular space. Trans-tight junction flux has been measured across large epithelial surfaces, but conductance across individual channels ...

    • Nuclear Receptor Binding Protein 1 Regulates Intestinal Progenitor Cell Homeostasis and Tumour Formation 

      Wilson, Catherine H; Crombie, Catriona; van der Weyden, Louise; Rust, Alistair G; Pardo, Mercedes; Gracia, Tannia; Yu, Lu; Choudhary, Jyoti; Poulin, Gino B; McIntyre, Rebecca E; Winton, Douglas J; March, H Nikki; Arends, Mark J; Fraser, Andrew G; Poulogiannis, George; Adams, David J. (Nature Publishing Group, 2012)
      Genetic screens in simple model organisms have identified many of the key components of the conserved signal transduction pathways that are oncogenic when misregulated. Here, we identify H37N21.1 as a gene that regulates ...