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Age-related decline in white matter tract integrity and cognitive performance: A DTI tractography and structural equation modeling study
(Elsevier BV, 2012)
Age-related decline in microstructural integrity of certain white matter tracts may explain cognitive decline associated with normal aging. Whole brain tractography and a clustering segmentation in 48 healthy individuals ...
Local white matter geometry from diffusion tensor gradients
(Elsevier BV, 2010)
We introduce a mathematical framework for computing geometrical properties of white matter fibres directly from diffusion tensor fields. The key idea is to isolate the portion of the gradient of the tensor field corresponding ...
White matter tract abnormalities between rostral middle frontal gyrus, inferior frontal gyrus and striatum in first-episode schizophrenia
(Elsevier BV, 2013)
Background—Previous studies have shown that frontostriatal networks, especially those involving dorsolateral prefrontal cortex (DLPFC) and ventrolateral prefrontal cortex (VLPFC) mediate cognitive functions some of which ...
Predicting inter-hemispheric transfer time from the diffusion properties of the corpus callosum in healthy individuals and schizophrenia patients: A combined ERP and DTI study
(Elsevier BV, 2011)
Background—Several theories of schizophrenia have emphasized the role of aberrant neural timing in the etiology of the disease, possibly as a consequence of conduction delays caused by structural damage to the white-matter ...
Stochastic tractography study of Inferior Frontal Gyrus anatomical connectivity in schizophrenia
(Elsevier BV, 2011)
Background—Abnormalities within language-related anatomical structures have been associated with clinical symptoms and with language and memory deficits in schizophrenia. Recent studies suggest disruptions in functional ...
Auditory verbal hallucinations and the interhemispheric auditory pathway in chronic schizophrenia
(Informa UK Limited, 2014)
Objectives—The interhemispheric auditory pathway has been shown to play a crucial role in the processing of acoustic stimuli, and alterations of structural and functional connectivity between bilateral auditory areas are ...
Corpus Callosum Abnormalities and Their Association with Psychotic Symptoms in Patients with Schizophrenia
(Elsevier BV, 2010)
Background—Whilst the neuroanatomical underpinnings of the functional brain disconnectivity observed in patients with schizophrenia remain elusive, white matter fiber bundles of the brain are a likely candidate given that ...
Extensive white matter abnormalities in patients with first-episode schizophrenia: A diffusion tensor imaging (DTI) study
(Elsevier BV, 2013)
Background—Previous voxelwise Diffusion Tensor Imaging (DTI) investigations of white matter in first-episode schizophrenia (FESZ) have been limited to the analysis of Fractional Anisotropy (FA) and mean diffusivity (MD), ...
A diffusion tensor imaging study of the anterior limb of the internal capsule in schizophrenia
(Elsevier BV, 2010)
Introduction—Frontal-subcortical cognitive and limbic feedback loops modulate higher cognitive functioning. The final step in these feedback loops is the thalamo-cortical projection through the anterior limb of the internal ...
Multi-tensor investigation of orbitofrontal cortex tracts affected in subcaudate tractotomy
(Springer Science + Business Media, 2014)
Subcaudate tractotomy (SCT) is a neurosurgical lesioning procedure that can reduce symptoms in medically intractable obsessive compulsive disorder (OCD). Due to the putative importance the orbitofrontal cortex (OFC) in ...