Browsing SPH Scholarly Articles by Title
Now showing items 4558-4577 of 6362
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Plasma Folate, Vitamin B6, Vitamin B12, and Homocysteine and Pancreatic Cancer Risk in Four Large Cohorts
(American Association for Cancer Research, 2007)Folate deficiency induces DNA breaks and may alter cellular capacity for mutation and epigenetic methylation. Few studies have examined the influence of one-carbon nutrients on pancreatic cancer risk, although recent studies ... -
Plasma free 25-hydroxyvitamin D, vitamin D binding protein, and risk of breast cancer in the Nurses’ Health Study II
(Springer (part of Springer Nature), 2014)Prior prospective studies, including our own, have evaluated total plasma 25-hydroxyvitamin D [25(OH)D] and breast cancer risk with inconsistent results. However, recent studies suggest that some vitamin D functions may ... -
Plasma Gelsolin Depletion and Circulating Actin in Sepsis—A Pilot Study
(Public Library of Science, 2008)Background: Depletion of the circulating actin-binding protein, plasma gelsolin (pGSN) has been described in septic patients and animals. We hypothesized that the extent of pGSN reduction correlates with outcomes of septic ... -
Plasma Heme Oxygenase-1 Concentration in Relation to Impaired Glucose Regulation in a Non-Diabetic Chinese Population
(Public Library of Science, 2012)Background: Our previous study has recently shown that plasma heme oxygenase-1 (HO-1), a stress-responsive protein, is elevated in individuals with type 2 diabetes. The current study aimed to examine the association between ... -
Plasma Heme Oxygenase-1 Concentration is Elevated in Individuals with Type 2 Diabetes Mellitus
(Public Library of Science, 2010)Background: Circulating concentrations of heme oxygenase-1 (HO-1) have been recently reported to be elevated in several chronic disorders. However, no study has ever examined the association between circulating HO-1 ... -
Plasma homocysteine, dietary B vitamins, betaine, and choline and risk of peripheral artery disease
(Elsevier, 2014)Objective: Few studies have examined the roles of homocysteine and related nutrients in the development of peripheral artery disease (PAD). We examined the associations between plasma homocysteine, dietary B vitamins, ... -
Plasma Inflammatory Markers and the Risk of Developing Hypertension in Men
(John Wiley & Sons, Ltd, 2015)Background: Several cross-sectional, but few prospective, studies suggest that inflammation may be involved in the development of hypertension. We examined markers of inflammation—high-sensitivity C-reactive protein, ... -
Plasma insulin-like growth factor 1 is positively associated with low-grade prostate cancer in the Health Professionals Follow-up Study 1993–2004
(Wiley, 2011)The insulin-like growth factor (IGF) axis plays a role in growth and progression of prostate cancer. High circulating IGF-1 levels have been associated with an increased risk of prostate cancer. Results for IGF binding ... -
Plasma leptin concentrations and four-year weight gain among US men
(Springer Nature, 2001) -
Plasma leptin concentrations and obesity in relation to insulin resistance syndrome components among school children in Taiwan—The Taipei Children Heart Study
(Springer Nature, 2000)OBJECTIVE: Leptin, an adipose tissue-derived product of the obesity (OB) gene, is an important regulator of energy metabolism and may be associated with the occurrence of insulin resistance and diabetes in humans. The ... -
Plasma Leptin Levels in Children Hospitalized with Cholera in Bangladesh
(The American Society of Tropical Medicine and Hygiene, 2015)Vibrio cholerae, the cause of cholera, induces both innate and adaptive immune responses in infected humans. Leptin is a hormone that plays a role in both metabolism and mediating immune responses. We characterized leptin ... -
Plasma levels of acid-labile subunit, free insulin-like growth factor-1, and prostate cancer risk: a prospective study
(American Association for Cancer Research, 2010)Background: The acid-labile subunit (ALS) acts in the insulin-like growth (IGF) system by binding circulating IGF-I in a ternary complex with binding protein (IGFBP)-3 to prevent IGF-I from crossing the endothelial barrier. ... -
Plasma Levels of Fetuin‐A and Risk of Coronary Heart Disease in US Women: The Nurses' Health Study
(Blackwell Publishing Ltd, 2014)Background: Fetuin‐A may be involved in the etiology of coronary heart disease (CHD) through opposing pathways (ie, promoting insulin resistance and inhibiting ectopic calcification). We aimed to explicitly examine whether ... -
Plasma Levels of Persistent Organic Pollutants and Risk of Type 2 Diabetes: a Prospective Analysis in the Nurses’ Health Study and Meta-analysis
(National Institute of Environmental Health Sciences, 2013)Background: Prospective data regarding persistent organic pollutants (POPs) and risk of type 2 diabetes (T2D) are limited, and the results for individual POPs are not entirely consistent across studies. Objectives: We ... -
Plasma Magnesium and Risk of Ischemic Stroke Among Women
(American Heart Association, 2014)Background: and Purpose-Lower plasma magnesium levels may be associated with higher blood pressure and endothelial dysfunction, but sparse prospective data are available for stroke.Methods-Among 32 826 participants in the ... -
Plasma malondialdehyde as biomarker for oxidative stress: reference interval and effects of life-style factors.
(American Association for Clinical Chemistry, 1997) -
Plasma Neutrophil Elastase and Elafin Imbalance Is Associated with Acute Respiratory Distress Syndrome (ARDS) Development
(Public Library of Science, 2009)Background: We conducted an exploratory study of genome-wide gene expression in whole blood and found that the expression of neutrophil elastase inhibitor (PI3, elafin) was down-regulated during the early phase of ARDS. ... -
Plasma organochlorine levels and risk of non-Hodgkin lymphoma in a cohort of men
(Lippincott, Williams & Wilkins, 2010)Background: Environmental exposure to polychlorinated biphenyls (PCBs) and p,p'-dichlorodiphenyldichloroethylene (p,p'-DDE) has been associated with the risk of non-Hodgkin lymphoma. Methods: We conducted a case-control ... -
Plasma Pentraxin 3 Levels Do Not Predict Coronary Events but Reflect Metabolic Disorders in Patients with Coronary Artery Disease in the CARE Trial
(Public Library of Science, 2014)Chronic inflammation closely associates with obesity, metabolic syndrome, diabetes mellitus, and atherosclerosis. Evidence indicates that the immunomodulator pentraxin 3 (PTX3) may serve as a biomarker of these cardiometabolic ... -
Plasma Phospholipid Omega‐3 Fatty Acids and Incidence of Postoperative Atrial Fibrillation in the OPERA Trial
(Blackwell Publishing Ltd, 2013)Background: Long‐chain polyunsaturated omega‐3 fatty acids (n‐3 PUFA) demonstrated antiarrhythmic potential in experimental studies. In a large multinational randomized trial (OPERA), perioperative fish oil supplementation ...