Search
Now showing items 1-2 of 2
Genetic Susceptible Locus in NOTCH2 Interacts with Arsenic in Drinking Water on Risk of Type 2 Diabetes
(Public Library of Science, 2013)
Background: Chronic exposure to arsenic in drinking water is associated with increased risk of type 2 diabetes mellitus (T2DM) but the underlying molecular mechanism remains unclear. Objectives: This study evaluated the ...
Association Test Based on SNP Set: Logistic Kernel Machine Based Test vs. Principal Component Analysis
(Public Library of Science, 2012)
GWAS has facilitated greatly the discovery of risk SNPs associated with complex diseases. Traditional methods analyze SNP individually and are limited by low power and reproducibility since correction for multiple comparisons ...