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Now showing items 81-85 of 85
Investigating Host Protein Function and Developing Assays for Influenza Virus Infection
(2015-04-08)
With eight genomic segments encoding at least thirteen proteins, influenza virus can subvert a cell into a virus-producing factory. To study influenza infection, I utilize versatile fluorescent-based technologies to ...
Regulation of Effector CD8+ T Cells During Mycobacterium Tuberculosis Infection
(2015-05-18)
Approximately one-third of the world’s population is currently infected with Mycobacterium tuberculosis (Mtb), the bacillus that causes tuberculosis. Globally, it is the second leading cause of death by a single infectious ...
Enterococcus infection of Caenorhabditis elegans as a model of innate immunity
(2015-05-14)
The vast majority of metazoan species are invertebrates, which lack an adaptive immune system for defense against microbes. Instead, their innate immune system is sufficient for defense against pathogenic organisms, which ...
Molecular Details and Functional Analysis of RNA Binding by ESCRT-II
(2015-05-18)
Many RNAs show distinct localization patterns in cells with enrichment at particular subcellular sites or organelles. RNA localization is a highly conserved process that both spatially and temporally controls gene expression. ...
Pathogenic Potential ofCD4 T Cells in Autoimmune Diseases
(2015-05-22)
The molecular mechanisms governing T helper (Th) cell differentiation and function have revealed a complex network of transcriptional and protein regulators. Cytokines not only initiate the differentiation of CD4 T helper ...